The three-component formulation targets complementary contamination risks: Penicillin inhibits bacterial cell-wall synthesis in Gram-positive organisms, Streptomycin (an aminoglycoside) inhibits bacterial protein synthesis with broader Gram-negative coverage, and Amphotericin B disrupts fungal cell membranes to control yeast and mold contamination together providing broad-spectrum prophylactic protection for routine, non-critical cell culture work.
Antibiotic-Antimycotic Solution is a ready-to-use 100X cell culture supplement combining Penicillin G, Streptomycin, and Amphotericin B (Fungizone), formulated to provide broad-spectrum protection against bacterial and fungal contamination in mammalian cell culture.
| Chemical Name | Antibiotic-Antimycotic Solution (Penicillin/Streptomycin/Amphotericin B) |
| CAS Number | N/A (formulated mixture) |
| IUPAC Name | N/A (formulated multi-component mixture) |
| Molecular Formula | N/A (formulated mixture) |
| Molecular Weight | N/A g/mol |
Standard 100X supplement added to growth media to suppress bacterial and fungal contamination in non-critical cultures.
Provides broad contamination coverage when isolating and establishing primary cell cultures from tissue explants.
Used to protect valuable cell stocks during extended culture and cryopreservation workflows.
Widely used across research cell culture applications where antibiotic-free protocols are not required.
In Vitro Cell. Dev. Biol. Anim.
PLoS One
Methods Cell Biol.
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