Gentamicin exerts its bactericidal effect by binding irreversibly to the bacterial 30S ribosomal subunit, causing misreading of mRNA codons and blocking translocation of peptidyl-tRNA, thereby halting protein synthesis. As a fermentation product, gentamicin sulfate is not a single defined molecule but a complex of closely related components (gentamicin C1, C1a, C2, C2a, C2b), each requiring approximately five equivalents of sulfuric acid per mole of gentamicin base for salt formation --- which is why its composition is described as a formula range rather than a fixed molecular formula.
Gentamicin sulfate is a broad-spectrum aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. Supplied here as ready-to-use sterile-filtered aqueous solutions (10 mg/mL and 50 mg/mL), it is widely used both as a therapeutic antibacterial agent and as a cell culture selection/contamination-control reagent.
| Chemical Name | Gentamicin Sulfate (Aminoglycoside Complex) |
| CAS Number | 1405-41-0 |
| IUPAC Name | Gentamicin Sulfate (Aminoglycoside Antibiotic Complex, Sulfate Salt) |
| Molecular Formula | C21H43N5O7.H2SO4 |
| Molecular Weight | ~1,488.8 g/mol g/mol |
| Boiling Point | NA |
| Density | na |
| Refractive Index | na |
| Flash Point | na |
Our R&D centers specialize in the design and process development of complex heterocyclic and chiral molecules — mg to kg scale.